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10.1038/nature11079 Nature 136 LuJ.-X.QiangW.YauW.-M.SchwietersC

Continuous data collected from the participants over the 26 week treatment period was assessed using an ANCOVA model, using randomized treatment as a factor and baseline bodyweight as a covariate

Future research should prioritise long-term outcomes in high-risk groups, comparisons of physiological versus pharmacological dosages in healthy subjects, cost-effectiveness analyses, and adherence monitoring to inform clinical guidelines for the management and prevention of B12 deficiency