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Physical examination should include careful neck palpation to detect thyroid enlargement or nodules

Indeed, as it will be discussed below, serious concerns had been repeatedly raised on the actual PAC safety (Brune et al., 2015

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Khaleel B, Lunenfeld E, Kapelushnik J, Huleihel M (2022) Effect of Chemotherapy Cytarabine and Acute Myeloid Leukemia on the Development of Spermatogenesis at the Adult Age of Immature Treated Mice