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This beneficial effect was supposedly due to the increased expression of genes involved in biotic stress response ( PR1 ), ethylene biosynthesis and ROS scavenging including a GST (Tiwari et al., 2016)

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Histologically, congenital hyperinsulinism can be diffuse, where all beta cells are affected, or focal, where there is a focal area of adenomatosis ( Plasma incretin concentrations in both the fasting and fed state have been measured in patients with different forms of congenital hyperinsulinism

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