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To achieve GSH depletion in liver, we engineered an adeno-associated virus (AAV) vector encoding Chac1 fused to a Myc tag, driven by the thyroxine-binding globulin (TBG) promoter to achieve liver-specific overexpression of Chac1 (Figure 1B)

Medical records documenting elevated inflammatory markers, CT or MRI evidence of pancreatic necrosis, extended hospitalizations, and the development of subsequent gastroparesis create compelling evidence for causation in litigation

Nat Rev Endocrinol 18(5):273289 Chow LS (2018) Mitochondria in muscle and exercise

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Unlike national telehealth giants that treat you like a number, PURE is a locally owned and operated medical practice deeply rooted in the Midwest healthcare community