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Status and phase Conditions Treatments Study type Funder types Identifiers About This trial aims to asses if tirzepatide-induced weight loss will lead to metabolic and hormonal changes in hormone receptor-positive (HR+), human epidermal growth factor receptor-negative (HER2-), node-positive (N+) high risk early breast cancer patients with obesity or overweight, inhibiting the growth and survival of micrometastatic disease and leading to clearance of tumor-informed circulating tumor DNA (ctDNA) and freedom from the development of metastatic disease

Key highlights Microdosing involves administering smaller or sub-therapeutic doses of the medication to get potential benefits without affecting the physiological systems of your body

Common pathological processes in Alzheimer disease and type 2 diabetes: a review

Our findings indicate that surgery should remain an important treatment option for obesity and diabetes, says Dr

Subsequently, CPT1 catalyzes the association of long-chain fatty acyl-CoA with L-carnitine to generate acylcarnitine