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A total of 14%, 32%, and 47% of the patients achieved a successful outcome at 1, 2, and 6 months, respectively, while the percentages reaching a 50% decrease in VAS were 36%, 41%, and 47%, respectively, demonstrating a satisfactory effect

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Combination with Metformin or Metformin with SGLT-2 Inhibitors In a 26-week, double-blind, double-dummy trial (Trial 4, NCT02863419), 711 adult patients with type 2 diabetes mellitus on metformin alone or metformin with SGLT-2 inhibitors were randomized to RYBELSUS 14 mg once daily, liraglutide 1.8 mg subcutaneous injection once daily or placebo