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In the SUSTAIN-6 trial, participants achieved average A1C reductions of 1.52.0 percentage points by 30 weeks, with many stabilizing by week 20

The pathophysiology of neuropathic pain encompasses multiple factors, including both peripheral and central sensitization [3]

The selection of the transgenic 5xFAD mouse model in our study was based on its ability to recapitulate an AD-like phenotype achieved through the expression of APP and PSEN1 transgenes (Brody et al., 2017

All of the participants, across four countries, were classed as being overweight at the start of the trial

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