The difference is bioavailability
[PubMed] [PMC] Liang Y, Tang Z, Jiang Y, Ai C, Peng J, Liu Y, Chen J, Zhang J, Cai Z (2020) Serum metabolic changes associated with dioxin exposure in a Chinese male cohort
Similar results were obtained if fenofibrate was given directly to tumor bearing mice that had been vaccinated against a tumor-associated antigen (119)
Effect of a plant extract of fenugreek ( Trigonella foenum-graecum ) on testosterone in blood plasma and saliva in a double blind randomized controlled intervention study
Thyroid tumor warning: All semaglutide medications also carry an FDA boxed warning for a potential risk of thyroid C-cell tumors based on animal studies, although it is unknown whether this risk applies to humans