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Supplementary information Rights and permissions About this article Cite this article Wang, H., Du, Ys., Xu, Ws

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Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist

34 In our study we did not find the same associations with BMI and GLP-1 or glucagon z-scores and we found no significant differences between children with metabolic syndrome compared to without metabolic syndrome in regard to GLP-1, GIP or glucagon z-scores

Studies examining global DNA methylation in GHK-Cu-treated cells have identified altered methylation status at specific CpG sites within promoter regions of genes involved in matrix metabolism and inflammatory responses