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One prevailing theory is that tirzepatide is an imbalanced and biased GLP-1 RA with very low efficacy for recruitment of -arrestin, whilst is acting as an unbiased GIP agonist with full efficacy for -arrestin recruitment [51, 52]

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Cora Healths published materials cite the same trials with the same "individual results vary" and "not therapeutically equivalent" disclaimers

The pharmacy also ceased production of all GLP-1 drug products intended to be sterile