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Your schedule may pause or slow if you have side effects

To reach a dose of 8mg or 12mg, the titration process would take approximately 12 to 16 weeks of gradual, stepped increases

Possible Side Effects Most reactions are mild and limited to the skin surface: Transient burning or stinging at application site Redness, dryness, or itching Acneiform eruptions or folliculitis Tingling or rash Contact dermatitis (rare) Management tips: Use a gentle cleanser, avoid alcoholbased toners, and apply noncomedogenic moisturizer if needed

Editor's note: Lose It

Folic acid helps prevent birth defects known as neural tube defects, including spina bifida