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For eligible individuals particularly those with elevated BMI or weight-related metabolic risk doctor-supervised weight loss treatment may provide structured, safer alternatives to commercial programs

"Importantly, for individuals focused on losing weight, the goal is often to reduce fat, rather than muscle mass," he added

Studies have reported that gastrointestinal disturbances such as nausea, vomiting, diarrhea, and constipation are common (incidence rate 44 %, 30 %, 24 %, and 24 %, respectively [31]) and often dose- and time-dependent in patients with overweight or obesity [41,44,45]

Of course, a lot of extra hydration besides those treatments

These compounds now sit in a regulatory space where the restriction has lifted but the affirmative safety determination has not yet been made