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This distinction allows researchers to explore upstream metabolic regulation and cellular signaling mechanisms through a different experimental approach

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the authors recommended repurposing nitazoxanide for hepatic steatosis

Mimicking the in vivo environment by including extracellular matrix (ECM) components, three-dimensional (3D) architectural features, a heterogeneous cellular composition and incorporating fluid shear stress in an in vitro kidney model could improve prediction of injury after drug exposures

In severe cases, a deficiency can even lead to a swollen and inflamed tongue and mouth, known as glossitis