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Key updates include: Annual screening for overweight and obesity Confirmation of excess adiposity beyond BMI when feasible Clear recognition that 57% weight loss improves glycemia and cardiometabolic risk Importantly, pharmacologic obesity treatment now emphasizes: Individualized dose titration Balancing efficacy with tolerability Considering alternative agents when response plateaus GLP-1 receptor agonists and dual GIP/GLP-1 therapies now sit at the center of metabolic care

doi: 10.1161/01.cir.0000437739.71477.ee [DOI] [PMC free article] [PubMed] [Google Scholar] 95.U.S

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Editors note: An earlier version of this article was first published on July 3, 2023