On the other hand, DAM can also exert neuroprotective functions through TREM2 signaling, as evidenced by the finding that TREM2 deficiency exacerbates pathological TDP-43 inclusions, motor dysfunction, and neurodegeneration (Xie et al., 2022)
A 2016 review of 2 randomized clinical trials and 3 prospective studies concluded that oral B12 at 1,000 mcg a day was a safe and effective alternative to intramuscular injections
Jemni M, Zaman R, Carrick FR, Clarke ND, Marina M, Bottoms L, et al
Once phosphorylated, these transcription regulators could migrate into the nucleus of somatotroph cells, possibly impacting genes associated with growth hormone formation
Generally, nutrient infusion visits are done weekly until there is improvement and then reduced to maintenance bi-weekly, monthly or other customized to you