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Cell viability and cell proliferation were detected by Cell Counting Kit-8 (CCK-8)

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It is synthesized exclusively by micro-organisms (e.g., Lactobacillus spp ) (LeBlanc et al., 2013), which are also found in the gastrointestinal tract of herbivorous animals, where the synthesis of B12 occurs and the vitamin can be acquired in animal tissues

Furthermore, a significant decrease in TXNIP levels was observed after metformin treatment

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