Fatty Acid ester of Hydroxyl Fatty Acid (FAHFAs) are adipocyte derived lipokines that can improve insulin sensitivity by suppressing endogenous glucose production in liver through G i protein coupled receptors and enhance insulin action in adipocytes (155)
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These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), exenatide (Byetta, Bydureon BCise), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist