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Acknowledgements This open-access review paper was supported by The project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, is co-funded by the European Union, and the Erasmus+ Programme of the European Union, Key Action 2: Strategic Partnerships, Project no

Plenty of compounds that improved rodent memory went on to do nothing in people that's a well-worn path in dementia research, not a rare exception