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Maternal separation induces long-term oxidative stress alterations and increases anxiety-like behavior of male Balb/cJ mice

GLP-1 is notably produced by hindbrain PPG neurons, mainly in the nucleus tractus solitarius (NTS) and the medullary intermediate reticular nucleus (IRT) 4

We believe that the decreased expression of NF-B may be related to the reduction of free radicals in intestinal tissues

Conclusion: Intermittent fasting can offer benefits for individuals with type 2 diabetes, such as weight loss and improved insulin sensitivity

In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance, increased glucose levels, obesity, and cardiovascular disease), discussing whether IGF-1 replacement therapy could be a beneficial strategy for these patients