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During oxidative stress, NAC will increase GSH synthesis (Franco and Cidlowski, 2009
This is direct neurohormonal modulation
Correction of a glutathione deficiency in the ageing mosquito increases its longevity
1 Introduction Polycystic ovary syndrome (PCOS) represents one of the most complex endocrine-metabolic disorders affecting women of reproductive age, characterized by a collection of reproductive, metabolic, and psychological manifestations ( Beyond the classic triad of hyperandrogenism (HA), ovulatory dysfunction, and polycystic ovarian morphology, PCOS extends into domains of insulin resistance, dyslipidemia, chronic inflammation, and heightened oxidative stress (OS) ( Conventional therapeutic strategies, though effective in symptom control, remain largely palliative, targeting isolated components of this multifactorial syndrome ( Thus, this review critically examines the triadic potential of these agents, not as standalone supplements but as a synergistic bioactive cocktail targeting the redox-endocrine axis
GuRShiYHuangWLaoCZouZPanSet al
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