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The most prevalent antioxidant in the brain is glutathione, a tripeptide made up of cysteine, glutamate and glycine

the presence of Mn 2+ and Zn 2+ significantly enhances cGAS's sensitivity to dsDNA and increases downstream cGAMP production [265, 266, 293]

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In a rat tail model, UA treatment alleviated the puncture-induced reduction in disc height, the increase in Pfirrmann grade scores and disc histological destruction