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Molecular principles of metastasis: a hallmark of cancer revisited

Thus, CHAC1s role in inducing ER stress and ferroptosis highlights its potential as a therapeutic target to increase the efficacy of DTX in treating castration-resistant prostate cancer ( In vivo experiments confirmed that knocking down miR-432-5p in CAFs enhanced CHAC1 expression, increased ferroptosis, and improved the efficacy of docetaxel in reducing tumor growth

The highly anticipated results are expected to readout in September 2025 9

Consultation with a registered dietitian can help develop an appropriate eating plan that provides sufficient energy while supporting weight management goals

Deamidation occurs when asparagine and glutamine residues in the peptide chain lose their amide groups