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Health Affairs has a good breakdown of the activity

How Creatine Works Once you ingest creatine via a food or supplement, it is converted into and stored as creatine phosphate, a phosphagen that helps your body store more usable energy for short bursts of intense movement

No Phase III trials exist comparing these formulations head-to-head with placebo in a double-blind design

Jun 21 2021;9(6)doi:10.3390/healthcare9060779

Therefore, it should be taken into consideration that treating cancer patients with MET inhibitors can lead to defective chemotaxis of neutrophils, and tumor cells can escape from tumor killing [29]