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The study, published in the Journal of Clinical Investigation Insight , showed that each time overweight mice stopped and restarted GLP-1s, they dropped less and less weight compared to their original weight loss
Here's what Found's program is built on: - Lower doses of GLP-1s provide metabolic benefits with improved tolerability (Nature, 2025) - 94% reduction in diabetes progression in people with prediabetes (NEJM, 2017) - Improved insulin sensitivity in PCOS (Reproductive Sciences, 2022) - Cardiovascular benefits independent of weight (Annals of Internal Medicine, 2024) - Reduction in systemic inflammation (Cells, 2024) Our approach: Apply these research insights to early intervention, informed also by clinical practice and real-world patient outcomes
It is important to emphasise that Saxenda has no official indication for cholesterol management
A person with high-sensitivity GLP1R variants may experience pronounced gastric slowing even at lower doses, raising contraceptive risk more than someone with lower-sensitivity variants at the same dose
