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Titration Is Not Optional The starting dose and titration schedule are critical

doi: 10.1016/j.bcp.2018.07.027 73 LiNLiuB-WRenW-ZLiuJ-XLiS-NFuS-Pet al

By coupling brain-targeted nanocarriers with patient-specific metabolic fingerprints, a gene-matched, pathway-matched strategy is emergingpositioning riboflavin at the center of personalized, systems-level interventions for both rare flavoproteinopathies and common neurodegenerative disorders