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This population-specific safety evidence is more relevant for clinical application than data from exclusively healthy volunteers would be
10.1097/eja.0000000000000915 Eur
Genetic Factors Alteration of the Transsulfuration Pathway One of the classic alterations of the homocysteine metabolism is represented by the homozygous deficiency of CBS (Mudd et al, 1995)
What changes at 10mg is research capacity: the ability to run full concentration gradients, parallel experimental arms, and extended single-batch studies without the batch-change variability that limits multi-vial 5mg programmes
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