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In addition to fat metabolism, L-Carnitine may help improve muscle recovery by reducing exercise-induced muscle damage and supporting endurance capacity

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In patients with HCC, we found that the plasma acylcarnitine to free carnitine ratio, a marker of carnitine insufficiency, was significantly increased on day 14 of lenvatinib therapy initiation, and that the increase was apparently correlated with the change in fatigue severity on day 28 (Okubo et al., 2020)

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