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Female Sprague-Dawley rats (n=6 per group) weighing 200-300 g, of approximately 6-8 weeks of age are used as subjects for the experiments

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Roediger WE (1980) Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man

Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]

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