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3 Tirzepatide is a GIP and GLP-1 dual receptor agonist indicated as an adjunct to lifestyle modification to improve glycemic control in adults with type 2 diabetes mellitus (T2DM).4, 5, 6, 7, 8, 9, 10, 11, 12, 13 Tirzepatide enhances first and second phase insulin secretion, reduces postprandial glucagon concentration in a glucose-dependent manner, delays gastric emptying, decreases food intake and reduces body weight