Yes, certain medications promote weight gain and can counteract GLP-1 effects, including antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), some antidepressants (mirtazapine, paroxetine), corticosteroids, and diabetes medications like insulin or sulfonylureas
[1] [2] The Medicines and Healthcare products Regulatory Agency (MHRA) has approved this medication primarily for glycaemic control, while a higher dose formulation (Wegovy) is specifically licensed for weight management
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