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Shiitake mushrooms and fermented foods, like tempeh, natto, and sauerkraut can contain some vitamin B12

What the animal studies cannot tell us includes optimal human dosing, population-specific responses (elderly, children, pregnancy), long-term safety in humans, rare side effects that require large sample sizes to detect, and interactions with medications or medical conditions

No invasive techniques are used, and no anesthesia is required

With b12 deficiency there can be an enlargement of red blood cells called macrocytiosis

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