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10 Finally, the effect of GLP-1RAs on weight may contribute to an increase in insulin sensitivity and better control of blood glucose
For hair growth specifically, combining topical GHK-Cu with microneedling is supported by the strongest evidence as shown in the 2025 Kuceki study which achieved 26.5% regrowth with this combination approach
These are typically reserved for individuals with severe obesity and related health complications, as they involve major surgery
In the fall of 2025, several new indications are expected for GLP-1s such as: Injectable semaglutide (NN9931) for metabolic dysfunction-associated steatohepatitis (MASH) Injectable semaglutide (Wegovy) and tirzepatide (Zepbound) for heart failure with preserved ejection fraction (HFpEF) in patients with obesity Oral semaglutide (Rybelsus) for major adverse cardiovascular events (MACE) risk reduction in adults with type 2 diabetes (T2DM) and established CVD and/or CKD Moreover, we are closely monitoring the pipeline for oral GLP-1s
Wang B, Wang XP
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