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Expected contraindications will likely mirror existing semaglutide contraindications: personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia type 2 (MEN 2), active pregnancy, or severe pancreatitis history

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Testing is also useful when fatigue is severe

In the CY 2026 PFS proposed rule (90 FR 32352, 32503), we clarified that the patient must have a mental health condition diagnosis, but the billing practitioner does not need to be the practitioner who made the diagnosis