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In contrast, the two single mutants slr0236 and sll1545 exposed to high light showed (i) no accumulation of ROS and (ii) weaker glutathione responses, in agreement with their low susceptibility to high-light (Figures 3B,D,F,H)

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Role of glutathione in detoxification and cancer therapy

Secondly, we have shown that a neurotoxic product of TRP metabolism, 3-OHKY, predicts severity of clinical symptoms during the early phase of illness and before exposure to antipsychotic drugs (Condray et al., 2011)