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Our red blood cells carry oxygen to all parts of the body
2009 Sep;42(13-14):1431-7
The efficient delivery of PGC-1 siRNA to bladder cancer cells was achieved through the liposomal nanoparticles delivery system in this study, resulting in significant downregulation of the PGC-1 protein levels
Hepatic effects that are considered adverse include death, abnormal clinical chemistry parameters, obvious functional organ impairment, DNA and mitochondrial alteration, glutathione depletion, hepatocyte necrosis, enhanced replicative DNA synthesis, generation of reactive oxygen species, and increased peroxisome proliferation (in rodents) (Williams and Iatropoulos 2002)
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