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At the site of infarction, the endothelial adherent junctions are disrupted by ROS, cytokines, chemokines, thrombin, histamine, platelet-activating factor, vascular endothelial growth factor, and bradykinins [119]

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In response to the comment solicitation, we proposed adopting services that are established and paid under the PFS and designated as care management services as care coordination services for purposes of separate payment for RHCs and FQHCs