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The Bottom Line The appeal of needle-free GLP-1 options is understandable, but the current evidence does not support sublingual semaglutide drops or weight loss patches as effective alternatives to proven treatments

[DOI] [PubMed] [Google Scholar] 253.Zhu L, Dattaroy D, Pham J, Wang L, Barella LF, Cui Y, Wilkins KJ, Roth BL, Hochgeschwender U, Matschinsky FM, Kaestner KH, Doliba NM, Wess J

According to research published in the New England Journal of Medicine, GLP-1 medications like semaglutide significantly reduce appetite and body weight, making every calorie count

95% CI, 0.64-0.97)