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[They] have simply fluctuated between five to 10 pounds after a significant weight loss of 50 to 70 pounds. Because semaglutide is a peptide drug, and peptides are like messenger systems, Decotiis says the drug might be able to rewire appetite over time, giving people struggling with diabetes and weight loss a greater chance of improving their eating habits

Onset of Side Effects: Hours to Days Most people who experience side effects from semaglutide notice them within the first few hours to a couple of days after their injection