Front Bioeng Biotechnol
This not only saves excipient costs but also simplifies formulations and reduces the difficulty of quality control
ROS also interact with unsaturated fatty acids in phospholipids, and aldehydes such as 4-hydroxynonenal, 4-hydroxyhexanal, acrolein, and MDA are the most reactive compounds (169)
They found that the GO-PEG hybrid exhibited high drug loading and more release at acidic pH (5.8) because of two kinds of possible H-bonding between the drug and carrier, whereas at neutral pH (7.4), four kinds of H-bonding existed between the drug and carrier
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