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402 Indeed, the reduction in zinc levels in pancreatic intraepithelial neoplasia (PanIN) lesions and malignancy is attributed to the downregulation of Ras responsive element binding protein 1 (RREB-1) and the silencing of ZIP3
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Type 2 diabetes is caused by reduced insulin effect or production and also leads to rising blood glucose levels (image created with biorender.com)
doi:10.1006/bbrc.2000.2267
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