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(2014) Meta-analysis of methylcobalamin alone and in combination with prostaglandin E1 in the treatment of diabetic peripheral neuropathy
As a result, the benefits are delayed and far less effective
This cost-effectiveness makes them an attractive option for long-term management of B12 levels
The following criteria were considered: Full economic evaluations: cost-utility analysis, cost-effectiveness analysis, cost-benefit analysis Economic evaluations reporting incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life year/life years gained or cost per event avoided) Studies in patients with confirmed vitamin B12 deficiency Studies in English Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained
B12 deficiency Vitamin B12 is water-soluble and is naturally found in some foods, such as meat, fish, and dairy products
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