Microglia in the brain of the elderly are often characterized by increased activation and decreased regulatory status
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FPN caused hippocampal microglia and astrocytes to proliferate and become more active, potentially increasing inflammatory cytokine expression 14 , such as IL-6, TNF- , and IL-1 , which could exacerbate oxidative stress and inflammation 3
In women suffering from PCOS and overweight or obesity, a combination therapy with the GLP-1 RA semaglutide and metformin significantly improves body weight reduction, insulin resistance, menstrual irregularities and natural pregnancy rates, compared to metformin monotherapy [190]
Read the blog to see how lifestyle medicine strengthens GLP1 therapy: #LifestyleMedicine #GLP1 #RootCauseCare #EvidenceBasedMedicine #WholePersonHealth To view or add a comment, sign in Lifestyle Medicine a necessity for people on GLP 1 therapy American College of Lifestyle Medicine European Lifestyle Medicine Organization (ELMO) #lifestylemedicine #GLP1 #Obesity #Diabetes #obesityManagement #Lifestylemodification #SuzanNashashibi GLP1s and other new obesity medications can be gamechangingbut medication alone isnt the solution
