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During life, the BBB is subjected to perturbations and stresses from a wide range of endogenous or exogenous sources, which can promote brain health or can lead to brain pathologies
Lai HW, See CY, Chen JY, Wu VC
[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Anderson E.J., Vistoli G., Katunga L.A., Funai K., Regazzoni L., Monroe T.B., Gilardoni E., Cannizzaro L., Colzani M., De Maddis D., et al
10.1515/bchm3.1996.377.9.555 377 LonghiS.UverskyV
Through the above-mentioned ways, estrogens exert a vast range of biological effects in the cardiovascular, musculoskeletal, metabolism, immune, central nervous and reproductive systems (Heldring et al., 2007)
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