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While the 48-hour rule technically allows for a two-day shift, it is generally safer to stick to a one-day shift unless you have discussed it with your provider

Combining alcohol with semaglutide, which already creates dehydration risk through GI side effects and suppressed thirst, significantly increases the concentration of urine and UTI vulnerability

To learn more, they conducted a survey of roughly 2,000 people across four groups: people who are currently taking a GLP-1 drug for weight loss, people who have taken a GLP-1 drug in the past, people who are planning to take a GLP-1 drug, and people who havent and arent planning to take these drugs

One study also found that discontinuation due to side effects was higher among those taking oral semaglutide compared to those taking injectable semaglutide