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The R code used to generate the results is available in the github repository Author contributions MC and TM contributed equally to the work and are shared first authors

It is considered one of the main risk factors for the development of T2D, a metabolic disease characterized by insulin resistance and/or impaired secretion of this hormone, which leads to high blood glucose levels (Wysocki et al, 2024)

These sustained incretin biology studies have established Semaglutide as the reference long-acting GLP-1R agonist for studying the beta cell pharmacology of chronic incretin receptor occupancy and the adaptation dynamics of insulin secretory machinery under prolonged GLP-1R engagement

A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study