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Certain aquaporins allow the diffusion of metabolites in and out of the cell (Tsukaguchi et al., 1998, 1999

Role in creatine synthesis : Glycine is a key component in the synthesis of creatine, a molecule that provides energy to muscles and supports brain function

Techniques such as erythrocyte hitchhiking, where nanoparticles temporarily attach to red cell membranes, enable targeted delivery to specific organs while reducing systemic toxicity (Zhang et al., 2022)

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The higher the ROR value, the higher the risk of corresponding ADE of the drug, the stronger the signal intensity, and the greater the correlation between the target drug and the risk signal (adverse event)