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Monoamine oxidase inhibitors (MAOIs) are an antidepressant class that absolutely cannot be taken alongside or within 14 days of either phentermine or Adderall

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Rathke, C., Baarends, W

I dont believe there is a drug interaction but I would be very careful about thyroid function and very careful about watching A1C because if you're using LDN and bump up the LDN to what's considered weight loss dosing and you're still using a peptide to help reduce total body mass index you don't want someone trigger any thyroid issues or other issues

Bkdal et al., based on pharmacokinetic investigations, did not observe any hepatic impairment, regardless of severity, on the pharmacokinetics of orally administered semaglutide [60]