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Sitagliptin is a p-glycoprotein substrate, but does not inhibit p-glycoprotein mediated transport of digoxin

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SHORT ACTING GLP-1 RECEPTOR AGONISTS Exenatide (Byetta) is a synthetic exendin-4 that is a peptide originally isolated from the saliva of the Gila monster that has a 53% homology with human GLP-1 and is resistant to degradation by DPP-4 (22,282)

(16) studied 41 patients with GSSDs from 33 families and found that variants causing frameshift, premature-termination, or aberrant splicing were only observed in patients with moderate or severe clinical phenotypes