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Tirzepatide's efficacy and safety profile is well-established through the SURPASS clinical trial program, which demonstrated significant HbA1c reductions (up to 2.5% from baseline) and weight loss in patients with type 2 diabetes

Funding Open access funding provided by Universit degli Studi di Siena within the CRUI-CARE Agreement

GE2 treatment significantly reduced IL-13 levels in the dorsal hippocampus compared to vehicle (main effect of treatment: F (1,44) = 5.346, p 2 = 0.106, p = 0.025