Such findings suggest that alpha-cells may activate GLP-1 production as a compensatory mechanism to protect beta-cell mass and function
But a growing body of research, and a wave of real-world experience, suggests these drugs may have meaningful benefits for people with T1D too: lower daily insulin doses, flatter glucose curves on your CGM, and potentially better long-term protection for your heart and kidneys
We placed the larvae fish in Petri dishes and administered the different drugs at 28 hpf
While a wide range of pharmacological treatments and disease management regimens exist to treat these conditions with varying degrees of efficacy, a promising new drug class known as glucagon-like peptide 1 receptor agonists (GLP-1s) and combination incretins such as dual GLP-1/glucosedependent insulinotropic polypeptides (GLP-1/GIPs, a subcategory of GLP-1s) has attracted widespread attention and interest from providers and patients for its potential to treat both these and adjacent conditions, and especially to drive weight loss
In clinical trials, acute pancreatitis occurred at a rate of 0.23 patients per 100 years of exposure for tirzepatide versus 0.11 for comparator treatments
